ADAMTS-7 Exhibits Elevated Expression in Cartilage of Osteonecrosis of Femoral Head and Has a Positive Correlation with TNF-α and NF-κB P65

Figure 2

ADAMTS-7 and TNF-α are upregulated in ONFH patients. (a) Expression of ADAMTS-7 of cartilage samples of FNF patients and ONFH patients at different stages, assayed by immunohistochemistry. (b) Expression of TNF-α in different groups, examined by immunohistochemistry with anti-TNF-α serum. (c) Quantitative analysis of ADAMTS-7-positive area of each group. (d) Quantitative analysis of TNF-α area of each group. Statistically significant increases in the expression of ADAMTS-7 and TNF-α were observed in group II and group III compared with group I (, ). Significant increases in the ADAMTS-7 and TNF-α expression were observed in group III compared with group II (^#, ^##).

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