Reduced Serum Butyrylcholinesterase Activity Indicates Severe Systemic Inflammation in Critically Ill Patients

Figure 3

POCT-measured BChE activity during systemic inflammation remains disrupted, independent of the patient liver function. Box plots represent median values and 25%–75% percentile of the POCT-measured BChE activity ( measurements (a)) and standard laboratory tests for ASAT ( measurements (b)), ALAT ( measurements (d)), GGT ( measurements, f), AP ( measurements (h)) activity, total serum bilirubin concentration ( measurements (j)), and INR coagulation test ( measurements (l)) in patients with systemic inflammation associated with (liver disease) or without (no liver disease) hepatic dysfunction. Scatter plots represent the correlation degree between POCT-measured BChE activity and the corresponding ASAT (c), ALAT (e), GGT (g), AP (i) activity, bilirubin concentration (k), and INR (m). ASAT: aspartate aminotransferase; ALAT: alanine aminotransferase; GGT: gamma glutamyl transpeptidase; AP: alkaline phosphatase; INR: international normalized ratio. , , and (Mann-Whitney test); : Spearman correlation coefficient.