5′-Adenosine Monophosphate-Induced Hypothermia Attenuates Brain Ischemia/Reperfusion Injury in a Rat Model by Inhibiting the Inflammatory Response

Figure 4

AIH inhibits neuronal apoptosis in the infarcted brain. (a–e) Fluorescence results of the TUNEL assay in the sham, MCAO, NT, HT(1.0), and HT(0.5) groups. Bright green dots were deemed apoptotic cells. Scale bar = 50 μm. (f) Quantitative analysis of apoptotic cells 24 h after ischemia. TUNEL-positive cells were counted from 3 random 1 × 1 mm² areas. All values are the mean ± SEM. compared to the MCAO group, ^# compared to the NT group, and ^& compared to the HT(0.5) group.

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