Relation of Biomarkers of Inflammation and Oxidative Stress with Hypertension Occurrence in Lone Atrial Fibrillation

Table 4

Univariate Cox proportional hazard analysis for the association of biomarkers with the occurrence of hypertension in lone AF patients.

Biomarkers	Unadjusted Cox analysis			Biomarker predictive ability (per quartile increase)			Pairwise comparison of biomarker predictive ability (per quartile increase)
	HR	95% CI	value	-statistic	95% CI	value	-statistic	95% CI	value
CRP (quartiles)	2.35	(1.25–4.39)	0.008	0.763	0.627–0.899	0.004	1.62; (CRP versus oxLDL)	−0.02–0.23	0.1005
oxLDL (quartiles)	2.55	(1.33–4.89)	0.005	0.879	0.787–0.971	<0.001

HR: hazard ratio; CI: confidence interval.
1st, 2nd, 3rd, and 4th quartiles of biomarkers, respectively: CRP: <0.80 mg/L; 0.80 to <1.58 mg/L; 1.58 to <2.70 mg/L; ≥2.70 mg/L; oxLDL: <49.5 U/L; 49.5 to <61.5 U/L; 61.5 to <79.0 U/L; ≥79.0 U/L.