The Olive Oil-Based Lipid Clinoleic Blocks Leukocyte Recruitment and Improves Survival during Systemic Inflammation: A Comparative In Vivo Study of Different Parenteral Lipid Emulsions

Figure 5

Effect of different lipid treatments on LPS-induced leukocyte adhesion in flow chamber experiments. Microflow chambers were coated with P-selectin, ICAM-1, and CXCL1 and perfused with LPS-stimulated bone marrow neutrophils at constant flow. Leukocyte adhesion (adherent leukocytes per field of view) was assessed after pretreatment with or without Clinoleic, Lipofundin, or Smoflipid and compared to unstimulated and uncoated control flow chambers. Significant differences versus all other groups are indicated by the asterisk and between indicated groups by the pound key ().