Therapeutic Effect of Chenodeoxycholic Acid in an Experimental Rabbit Model of Osteoarthritis

Figure 5

The levels of MMP-1 (a), MMP-3 (b), IL-1β (c), and PGE₂ (d) in synovial fluid from knee joints were measured by ELISA. Each reported value is a mean ± SEM (); ^###, compared with the sham-operation group; , , and , compared with the model group. Similar results were observed in two separated experiments.

(a)

(b)

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(d)