Synergistic Stimulation with Different TLR7 Ligands Modulates Gene Expression Patterns in the Human Plasmacytoid Dendritic Cell Line CAL-1

Table 2

Top 10 functional groups.

Functional group	value
Cellular development, growth, and proliferation	<7.26–6.8
Hematological system development and function	<7.26–6.8
Cellular function and maintenance	<5.44–1.93
Cell death and survival	<5.72–6.36
Tissue morphology	<2.58–4.79
Infectious disease	<1.60–4.55
Immunological disease	<8.8–4.05
Cell-to-cell signaling and interaction	<1.20–5,89
Immune cell trafficking	<1.20–5,89
Inflammatory response	<1.20–6,74

CAL-1 cells were treated as described above (see Table 1). The table lists the 10 most upregulated functional groups as identified by IPA.