Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity

Figure 5

Adipose tissue inflammation at sacrifice. (a) Representative histological pictures of the visceral (gonadal) adipose tissue from different groups demonstrating an increase in the number of crown-like structures upon HFD-feeding which is not attenuated by polyphenols supplementation. (b) Quantification of crown-like structures (c) F4/80 and (d) MCP-1 gene expression confirm this phenotype. Expression of the IL-1β gene is not affected (e) in contrast to Tnf (f) which is significantly lower in the HFD+B group compared to HFD. Significant from HFD (, , and ).

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