Antileishmanial Activity and Inducible Nitric Oxide Synthase Activation by RuNO Complex

Figure 4

ICC scoring, nuclear staining, and relative quantification of iNOS mRNA of macrophages infected with L. amazonensis and treated with RuNO complex (60 μM) for 24 h. (a) Akt, (b) phosphorylated Akt (P-Akt), (c) NF-κB, (d) phosphorylated p65 (P-p65), (e) iNOS, (f) iNOS mRNA, and (g) immunocytochemical staining. [Values represent the mean ± SEM of three independent experiments (). [ different from control infected, different from treated control, and different from control.]

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