Ethanol Extract of Sanguisorbae Radix Inhibits Mast Cell Degranulation and Suppresses 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions

Figure 2

Effects of ESR on scratching behavior and ear thickness in AD mouse skin lesions. (a) Experimental induction of AD mouse skin lesions. (b) Ear thickness was measured with a dial thickness gauge. Results are expressed as the mean ± standard error of the mean (SEM) (). Vehicle, negative control; control, DNCB + vehicle; ESR, DNCB + 200 mg/kg ESR; Dexa., DNCB + 1 mg/kg dexamethasone treated group. , , and versus vehicle; and versus control.

(a)

(b)