Ethanol Extract of Sanguisorbae Radix Inhibits Mast Cell Degranulation and Suppresses 2,4-Dinitrochlorobenzene-Induced Atopic Dermatitis-Like Skin Lesions

Figure 3

Effects of ESR on epidermal thickness and eosinophil accumulation in DNCB-induced AD mouse skin lesions. (a) H&E stained AD mouse skin lesions (20x, scale bar = 100 μm) and image of amplification sections (right image of group, scale bar = 20 μm). (b) Determination of epidermal thickness. (c) Number of eosinophils per mm section. Epidermal thickness in H&E stained sections was measured under a microscope and the number of eosinophils accumulations is expressed as the average total count in five fields of 100 μm². versus control.

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