Plasma MicroRNA-21 Predicts Postoperative Pulmonary Complications in Patients Undergoing Pneumoresection
Table 4
Distribution of primary and secondary endpoints during 1-year follow-up and their relationships with miRNA-21 fold changes based on univariate logistic regression.
Category
(%) or mean ± SD
OR
95% CI
value
PPCs
38 (10.3)
4.58
3.16–6.87
<0.001
Microatelectasis
3 (0.8)
Bronchospasm
10 (2.7)
Hypoxemia
4 (1.0)
Atelectasis
6 (1.6)
Hypercarbia
5 (1.4)
Pleural effusion
5 (1.4)
Pneumonia
3 (0.8)
Respiratory failure
2 (0.5)
ARDS
6 (1.6)
1.56
1.15–4.87
0.03
Extrapulmonary complications
20 (5.4)
3.62
2.26–5.81
<0.001
Sepsis
8 (2.2)
Severe sepsis
8 (2.2)
Septic shock
4 (1.1)
ICU stay
7.0 ± 3.2
6.54
2.26–18.19
<0.001
Death in 30 days
3 (0.8)
6.17
2.11–18.08
<0.001
Death in 1 year
6 (1.6)
7.30
2.76–19.28
<0.001
PPC: postoperative pulmonary complication; ARDS: acute respiratory distress syndrome; ICU: intensive care unit.
