Circulating Memory T Follicular Helper Cells in Patients with Neuromyelitis Optica/Neuromyelitis Optica Spectrum Disorders

Figure 2

Analysis of the percentages and numbers of different subsets of memory Tfh, CCR7⁻ memory Tfh, and CCR7⁺ memory Tfh cells in AQP4 Ab-seropositive and AQP4 Ab-seronegative patients. ((a)–(c)) The percentages of memory Tfh, ICOS⁺ memory Tfh, and PD-1⁺ memory Tfh cells in AQP4 Ab-seropositive and AQP4 Ab-seronegative patients. ((d)–(f)) The numbers of memory Tfh, ICOS⁺ memory Tfh, and PD-1⁺ memory Tfh cells in AQP4 Ab-seropositive and AQP4 Ab-seronegative patients. ((g)–(i)) The percentages of CCR7⁻, CCR7⁻ICOS⁺, and CCR7⁻PD-1⁺ memory Tfh cells in AQP4 Ab-seropositive and AQP4 Ab-seronegative patients. ((j)–(l)) The numbers of CCR7⁻, CCR7⁻ICOS⁺, and CCR7⁻PD-1⁺ memory Tfh cells in AQP4 Ab-seropositive and AQP4 Ab-seronegative patients. ((m)–(o)) The percentages of CCR7⁺, CCR7⁺ICOS⁺, and CCR7⁺PD-1⁺ memory Tfh cells in AQP4 Ab-seropositive and AQP4 Ab-seronegative patients. ((p)–(r)) The numbers of CCR7⁺, CCR7⁺ICOS⁺, and CCR7⁺PD-1⁺ memory Tfh cells in AQP4 Ab-seropositive and AQP4 Ab-seronegative patients.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)

(k)

(l)

(m)

(n)

(o)

(p)

(q)

(r)