Radiotherapy Suppresses Bone Cancer Pain through Inhibiting Activation of cAMP Signaling in Rat Dorsal Root Ganglion and Spinal Cord

Figure 2

Radiotherapy alleviated TCI-induced tibia bone destruction. Radiographic images were taken on the 17th day after TCI. (a, b, c) Representative bone destruction and tumor growth in groups of sham (a), TCI + sham radiotherapy (b), and TCI + radiotherapy (c). Data are summarized in (d). Eight rats were included in each group. Arrows in (a–c) point to the areas of the bone destruction. versus sham; versus TCI + sham; versus sham.

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