Circulating Calreticulin Is Increased in Myelofibrosis: Correlation with Interleukin-6 Plasma Levels, Bone Marrow Fibrosis, and Splenomegaly

Figure 3

Correlation between IL-6 plasma levels and BM fibrosis, splenomegaly, number of circulating CD34⁺ cells, and hemoglobin values. Irrespective of mutational status, IL-6 plasma levels correlated with BM fibrosis (; ), splenomegaly (; ), and the absolute number of circulating CD34⁺ cells (; ) and negatively correlated with hemoglobin values (; ); (a, b, c, and d, resp.). -axis of (a) shows BM fibrosis scale.

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