Research Article
Plasma Leptin Is Elevated in Acute Exacerbation of Idiopathic Pulmonary Fibrosis
Table 1
Baseline clinical characteristics of patients with AE-IPF and S-IPF.
| | Clinical characteristics | | AE-IPF patients | S-IPF patients | value |
| | Gender (male/female) | 62 | 23/7 | 28/4 | 0.272 | | Age (years) | 62 | 64.97 ± 9.36 | 67.87 ± 8.42 | 0.206 | | Smoker (yes/no) | 59 | 9/21 | 11/18 | 0.528 | | BMI (kg/m2) | 45 | 24.59 ± 2.71 | 24.15 ± 2.89 | 0.679 | | Leptin (ng/mL) | 62 | 21.60 ± 11.97 | 11.57 ± 8.54 | <0.001 | | KL-6 (U/mL) | 56 | 2632.96 ± 1181.50 | 1264.10 ± 862.51 | <0.001 | | WBC (×109) | 62 | 10.10 ± 5.42 | 8.71 ± 3.82 | 0.244 | | LDH (U/L) | 62 | 381.07 ± 153.68 | 241.13 ± 62.84 | <0.001 | | ESR (mm/h) | 62 | 40.30 ± 27.50 | 30.38 ± 27.40 | 0.171 | | CRP (mg/L) | 62 | 56.74 ± 63.08 | 20.7 ± 38.27 | 0.008 | | ALB (g/L) | 62 | 33.97 ± 4.12 | 37.73 ± 5.07 | 0.002 | | PaO2/FiO2 | 62 | 204.53 ± 73.22 | 327.76 ± 66.66 | <0.001 | | MV (user/nonuser) | 62 | 9/21 | 1/31 | 0.004 | | Survival state (dead/censor) | 62 | 26/4 | 7/25 | <0.001 |
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