Serum Amyloid A Promotes E-Selectin Expression via Toll-Like Receptor 2 in Human Aortic Endothelial Cells

Figure 6

Summary of the possible mechanism for induction of E-selectin by SAA via TLR2. SAA may stimulate the expression of adhesion molecules including E-selectin through downstream signaling pathways such as NF-κB and TNF-α via TLR2.