mTORC1-Activated Monocytes Increase Tregs and Inhibit the Immune Response to Bacterial Infections

Figure 2

Bacterial number in the blood and survival curves of mice infected with E. coli. (a) The residual bacteria number in TSC1 KO mice is higher than in WT mice after E. coli infection (0⁷ cells/mouse) (three mice per group, two representative experiments). (b) The survival curves of mice after E. coli infection (6–8 mice per group, four representative experiments). (c) The concentration of various cytokines in the serum of WT and TSC1 KO mice after 6 h bacterial infection by ELISA. , , and compared to WT mice or between the indicated groups. values were determined using Student’s -tests.

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