IL-6 Inhibition Reduces STAT3 Activation and Enhances the Antitumor Effect of Carboplatin

Figure 3

Synergistic effect of CBP and IL-6 blockade on LoVo cell survival: (a) LoVo cells were treated with 20 μg/mL CBP and/or 500 μg/mL IL-6 neutralizing antibody (Ab) or PBS. Cells were stained with DAPI (0.2 μg/mL) and morphological change was examined after 72 h under microscope (100x). (b) LoVo cells were treated with 20 μg/mL CBP and/or 500 μg/mL IL-6 neutralizing antibody (Ab) or PBS. Cells were collected for the detection of viability using CCK-8 kit. ; .

(a)

(b)