miR-155 Regulated Inflammation Response by the SOCS1-STAT3-PDCD4 Axis in Atherogenesis

Figure 2

The levels of cytokines IL-6, TNF-α, and IL-10 in RAW264.7 cells after ox-LDL treatment and atherosclerotic mice. (a) ox-LDL induced the expression of IL-6, TNF-α, and IL-10 for 24 h at indicated dose was determined by qPCR: , relative to control, , relative to 5 μg/mL ox-LDL group; , relative to 10 μg/mL ox-LDL group. (b) The plasma levels of IL-6, TNF-α, and IL-10 of c57 mice WT, ApoE^−/− ND, and ApoE^−/− HFD were detected by the ELISA kit (): , relative to c57 mice WT; , relative to ApoE^−/− ND.

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(b)