Research Article

Systemic Immune Activation Profiles of HIV-1 Subtype C-Infected Children and Their Mothers

Table 1

Demographic data of paired mothers and their children.

Mothers
Median (range)
Children
Median (range)

Age27 years
(20–44)
13 months
(2–71)
Circulating CD4+ T cell count
(cells/μL blood)
330
(115–744)
774
(22–2,856)
CD4+ T cells (%)22
(7–37)
18
(0.9–45)
Circulating CD8+ T cell count
(cells/μL blood)
740
(265–2,942)
1,675
(181–6,301)
CD8+ T cells (%)53
(32–77)
43
(18–67)
CD4/CD8 ratio0.4
(0.1–1)
0.5
(0.1–2)
HIV-viral load
(copies/mL blood)
61,000
(240–3,400,000)
980,000
(440–50,000,000)

Available data from 33 patients.
Available data from 32 patients.