IL-33 Effect on Quantitative Changes of CD4⁺CD25^highFOXP3⁺ Regulatory T Cells in Children with Type 1 Diabetes

Table 2

The status of CD4⁺CDFOXP3⁺ and CD4⁺CDFOXP3⁺ST2⁺ Treg cells after in vitro treatment with IL-33 in patients with type 1 diabetes.

	CD4^+CDFOXP3^+ (%)	CD4^+CDFOXP3^+ST2^+ (%)	MFI of FOXP3 among CD4^+CDFOXP3^+ cells	MFI of ST2 among CD4^+CDFOXP3^+ cells
Nonstimulated	2.8 (0.8/4.7)	0.85 (0.4/1.8)	2.1 (0.8/5.81)	4.92 (1.5/6.87)
IL-33 stimulated	6.35 (2.0/8.1)	2.05 (0.6/4.1)	4.06 (1.98/7)	5.54 (3.19/8.49)
	0.0004	0.0019	0.007	0.02

MFI: Mean Fluorescence Intensity.
Differences were calculated with the nonparametric Wilcoxon test.
Data are presented as median and 10th/90th percentile.