Apoptosis of Endothelial Cells by 13-HPODE Contributes to Impairment of Endothelial Barrier Integrity

Figure 9

Mean normalized endothelial resistance across time during media control (), 150 μM 13-HPODE (), and 150 μM 13-HPODE + 1 mM N-acetylcysteine (NAC) () exposure is displayed in Figure 9. Resistance of BMEC monolayer across time for each treatment group (control, 13-HPODE, and 13-HPODE + NAC) is normalized relative to time 0. Significance of differences in resistance across time between treatment groups was tested by a two-way repeated measures ANOVA and adjusted by Bonferroni’s multiple comparisons test. An asterisk () represents significance declared at . There were no significant differences detected between media control and 13-HPODE + 1 mM NAC.