Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF-κB and Downregulation of COX-2/iNOS

Figure 3

Anti-inflammatory effect of PAO on xylene-induced ear edema in mice. Indo: indomethacin (10 mg/kg); PAO-L: low dose of PAO (10 mg/kg); PAO-M: medium dose of PAO (20 mg/kg); PAO-H: high dose of PAO (40 mg/kg). Ear edema degree (%) was represented as the ratio of the difference in weight between the right and left ear of the same animal. Data were expressed as means ± SEM. (), and versus the vehicle group.