Patchoulene Epoxide Isolated from Patchouli Oil Suppresses Acute Inflammation through Inhibition of NF-κB and Downregulation of COX-2/iNOS

Figure 4

Anti-inflammatory effect of PAO on acetic acid-induced vascular permeability in mice. Indo: indomethacin (10 mg/kg); PAO-L: low dose of PAO (10 mg/kg); PAO-M: medium dose of PAO (20 mg/kg); PAO-H: high dose of PAO (40 mg/kg). The peritoneal vascular permeability was represented by the amount of Evans blue leaked into the abdominal cavity and measured by the absorbance of the supernatant at 590 nm. Data were expressed as means ± SEM. (), , and versus the vehicle group.