CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis

Figure 2

Decreased CNS demyelination in mice treated CpG-A during EAE. (a) Representative Luxol fast blue (LFB) staining of spinal cord sections from MOG-immunized mice treated with PBS or CpG-A to visualize demyelinization (arrows). Images are representative of one experiment out of three. (b) Quantification of spinal cord demyelination at day 20 after immunization in mice treated with PBS or CpG-A. Depicted are means ± sem in one representative of two. ; , two-tailed Mann–Whitney test.

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