CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis

Figure 3

Decreased CNS lymphocyte infiltration in mice treated with CpG-A during EAE. (a) Representative images of spinal cross sections at peak of disease in specific groups (indicated). Stained CD4⁺ T cells are shown. Images are representative of one experiment out of three; mice per group. Quantification of spinal cord immune-cell infiltration at day 20 after immunization in mice treated with PBS or CpG-A, CD4⁺ cells. (b) CD11b⁺/CD11c⁺. (c) Showed is the mean ± sem of two independent experiments; per group. , two-tailed Mann–Whitney test. .

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