Research Article
Differential Effects of Angelicin Analogues on NF-κB Activity and IL-8 Gene Expression in Cystic Fibrosis IB3-1 Cells
Table 2
IC50 values calculated after 48 h from treatment of IB3-1 cells with serial dilutions of TMA derivatives.
| | Derivative | IC50 (48 h) |
| | 1 | >800 μM | | 2 | >800 μM | | 3 | >800 μM | | 4 | >800 μM | | 5 | 485.89 μM | | 6 | 454.35 μM | | 7 | >800 μM | | 8 | 397.87 μM | | 9 | >800 μM | | 10 | <50 μM | | 11 | 181.78 μM | | 12 | >800 μM | | 13 | >800 μM | | 14 | >800 μM | | 15 | >800 μM | | 16 | >800 μM | | 17 | 193.07 μM | | 18 | >800 μM | | 19 | 131.12 μM | | 20 | 154.43 μM | | 21 | 677.87 μM | | 22 | 179.92 μM | | 23 | 451.66 μM | | 24 | 196.53 μM | | 25 | 551.23 μM | | 26 | 90.84 μM | | 27 | >800 μM | | 28 | >800 μM | | 29 | >800 μM | | 30 | >800 μM | | 31 | >800 μM | | 32 | >800 μM | | 33 | >800 μM | | 34 | >800 μM | | 35 | 137.31 μM | | 36 | >800 μM | | 37 | >800 μM | | 38 | 505.81 μM |
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