Challenging a Misnomer? The Role of Inflammatory Pathways in Inflammatory Breast Cancer

Figure 2

Schematic representation of important inflammatory pathways underpinning communication between IBC cells (tumor cells and cancer stem cells) and major cell types constituting the tumor microenvironment (mesenchymal stem cells, tumor-associated macrophages, and CD8-positive T cells are shown). Arrows indicate the cross talk of inflammatory mediators secreted by the indicated cell types to promote IBC progression.