Role of Cathepsin S in Periodontal Inflammation and Infection

Figure 3

(a) CTSS mRNA expression in gingival biopsies of rats with ligature-induced experimental periodontitis at 6, 8, and 12 d, as compared to that of healthy controls. Mean ± SEM ( per group and time point); significant () difference between groups. (b) CTSS mRNA expression in human gingival biopsies from periodontally healthy and periodontitis sites. Mean ± SEM ( per group); significant () difference between groups. (c) CTSS protein in human gingival biopsies from periodontally healthy or periodontitis sites, as revealed by immunohistochemistry. Representative images of biopsies from one healthy individual and one periodontitis patient are shown.

(a)

(b)

(c)