Research Article
Effects of FTY720 on Lung Injury Induced by Hindlimb Ischemia Reperfusion in Rats
Table 1
Arterial blood gases at the end of reperfusion (, ).
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Rats were divided into five groups: groups SM, IR, F3, F5, and F10. The rats in group SM received sham operation and bilateral limb IR (ischemia 3 h/reperfusion 3 h) in group IR. The rats in groups F3, F5, and F10 were treated with FTY720 3 mg/kg/d, 5 mg/kg/d, and 10 mg/kg/d, respectively, for 7 consecutive days before limb IR. Upon 3 h reperfusion, arterial blood gases were analyzed. PaO2: arterial partial pressure of oxygen; PaCO2: arterial partial pressure of carbon dioxide; BE: base excess. versus group SM; # versus group IR. |