A Double-Blinded Randomized Study Investigating a Possible Anti-Inflammatory Effect of Saxagliptin versus Placebo as Add-On Therapy in Patients with Both Type 2 Diabetes And Stable Coronary Artery Disease

Figure 1

The figure shows RQ values of IL-10 from (a) unstimulated PBMCs, (b) LPS-stimulated PBMCs, and (c) circulating leukocytes at baseline and after 3 months in the two randomized groups. The median values are given, with 25 and 75 percentiles depicting the spread. Δp denotes relative differences in change between the groups.  depicts significant intragroup change in RQ value. for intragroup difference from baseline to 3 months.

(a) Unstimulated PBMCs

(b) LPS-stimulated PBMCs

(c) Circulating leukocytes