Platelet-Released Growth Factors Induce Differentiation of Primary Keratinocytes

<div>The IL-6 receptor is not involved in the PRGF-mediated modulation of differentiation markers in keratinocytes. PRGF stimulation of primary human keratinocytes caused a reduced keratin 1 and keratin 10 gene expression and an induced transglutaminase-1 and involucrin gene expression. 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Mediators of Inflammation

fig5

Figure 5

Figure 5: Platelet-Released Growth Factors Induce Differentiation of Primary Keratinocytes 