Aloperine Protects Mice against DSS-Induced Colitis by PP2A-Mediated PI3K/Akt/mTOR Signaling Suppression

<div>Aloperine inhibits apoptosis in T-cells. (a) Western blotting was used to assess the expressions of cell apoptosis-related proteins (Bax, Bcl-2, and cleaved caspase-3) in Jurkat cell treatment with aloperine (0, 0.25, 0.5, and 1 mM) for 24 h. (b) Western blotting analysis of Mcl-1, Bcl-2, and cleaved caspase-3 expressions in mouse naïve T-cells following 24 h of treatment with aloperine (0.25 mM). 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Mediators of Inflammation

fig4

Figure 4

Figure 4: Aloperine Protects Mice against DSS-Induced Colitis by PP2A-Mediated PI3K/Akt/mTOR Signaling Suppression 