Research Article

Curcumin Attenuation of Wear Particle-Induced Osteolysis via RANKL Signaling Pathway Suppression in Mouse Calvarial Model

Figure 1

Curcumin prevented PMMA particle-induced mouse calvarial osteolysis. (a) Representative 3D μCT reconstructed images of the calvaria in each group (/group). Measured (b) BMD, (c) trabecular BV/TV ratio, (d) number of pores, and (e) the percentage of total porosity within the ROI from each sample (/group; versus the PBS group; versus the PBS group; # versus the PMMA group).
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