Interleukin 35 Polymorphisms Are Associated with Decreased Risk of Premature Coronary Artery Disease, Metabolic Parameters, and IL-35 Levels: The Genetics of Atherosclerotic Disease (GEA) Study
Table 2
Cardiovascular risk factors prevalence in the study population.
Control ()
Premature CAD ()
Total cholesterol > 200 mg/dL (%)
36.3
20.3
<0.001
LDL-cholesterol ≥ 130 mg/dL (%)
29.2
16.1
<0.001
Hypoalphalipoproteinemia (%)
49.3
67.2
<0.001
Hypertriglyceridemia (%)
42.8
56.2
<0.001
Non-HDL-cholesterol > 160 mg/dL (%)
26.0
19.5
<0.001
Obesity (%)
26.1
35.0
<0.001
Abdominal obesity (%)
77.6
83.6
<0.001
Type 2 diabetes mellitus (%)
0
35.4
<0.001
Hyperinsulinemia (%)
45.8
71.4
<0.001
Insulin resistance (%)
44.2
77.0
<0.001
Metabolic syndrome (%)
29.7
71.9
<0.001
Hypertension (%)
5.7
68.1
<0.001
High visceral adipose tissue (%)
49.8
64.6
<0.001
Current smoking status (%)
23.5
11.6
<0.001
Hypoadiponectinemia (%)
40.0
56.5
<0.001
High sensitivity C reactive protein ≥ 3 mg/L (%)
23.6
21.3
0.114
Hyperuricemia (%)
16.8
35.9
<0.001
Data is shown as percentage. Comparisons were made using Chi square analysis. CAD: coronary artery disease, LDL: low density lipoprotein, and HDL: high density lipoprotein.
