Association Study of Tumor Necrosis Factor Receptor 1 (TNFR1) Gene Polymorphisms with Schizophrenia in the Polish Population

Table 2

Genotype and allele distributions for the TNFR1 (rs4149576, rs4149577, and rs1860545) SNPs in patients with and without family history of schizophrenia and suicide attempts.

Polymorphisms	N (%)
	Genotype					Allele
rs4149576	T/T	C/T	C/C	χ^2	p	T	C	χ^2	p
With family history	24 (25)	48 (51)	23 (24)	0.41	0.81	96 (49)	94 (51)	0.23	0.67
Without family history	84 (29)	142 (48)	67 (23)			276 (47)	310 (53)
With suicide attempts	17 (23)	41 (55)	16 (22)	1.64	0.43	75 (51)	73 (49)	0.12	0.72
Without suicide attempts	91 (29)	149 (47)	74 (24)			331 (53)	297 (47)
rs4149577	A/A	A/G	G/G	χ^2	p	A	G	χ^2	p
With family history	31 (33)	48 (50)	16 (17)	0.09	0.95	110 (58)	80 (42)	0.01	0.92
Without family history	91 (31)	153 (52)	49 (17)			335 (57)	251 (43)
With suicide attempts	23 (31)	40 (54)	11 (15)	0.28	0.86	86 (58)	62 (42)	0.01	0.90
Without suicide attempts	99 (32)	161 (51)	54 (17)			359 (57)	269 (43)
rs1860545	G/G	G/A	A/A	χ^2	p	A	G	χ^2	p
With family history	26 (27)	46 (49)	23 (24)	0.47	0.78	92 (48)	98 (52)	0.29	0.58
Without family history	70 (24)	147 (50)	76 (26)			299 (51)	287 (49)
With suicide attempts	17 (23)	41 (55)	16 (22)	1.24	0.53	73 (49)	75 (51)	0.03	0.84
Without suicide attempts	79 (25)	152 (48)	83 (27)			318 (51)	310 (49)