Morita-Baylis-Hillman Adducts Display Anti-Inflammatory Effects by Modulating Inflammatory Mediator Expression in RAW264.7 Cells

Figure 6

Effects of A2CN, A3CN, and A4CN compounds on inflammatory cytokine production: IL-1 (a), IL-6 (b), and TNF-α (c). CTR means cells without LPS and MBHA compound incubation. LPS, cells incubated with LPS (1 μg/mL). Cells were incubated with A2CN, A3CN, or A4CN (2.5–20 μM) in the presence of LPS (1 μg/mL) for 22 h, as indicated. Reported values are the mean ± SEM of three independent experiments in triplicate. The dates were analyzed by ANOVA followed by Newman-Keuls post hoc test. ^#, ^###, compared to CTR group. , compared to LPS + MBHA compound groups.

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