Research Article

Cytokine Kinetics in Febrile Neutropenic Children: Insights on the Usefulness as Sepsis Biomarkers, Influence of Filgrastim, and Behavior of the IL-23/IL-17 Pathway

Table 2

General data (N, %). IQR: interquartile range.

N35
Age (years, median, IQR)5.84 (3.7–10.3)
Male10 (28.6%)
Received antibiotics35 (100%)
Diagnoses
 Acute lymphocytic leukemia6 (17.1%)
 Acute myelogenous leukemia3 (8.6%)
 Non-Hodgkin’s lymphoma6 (17.1%)
 Wilms’ tumor4 (11.4%)
 Primitive neuroectodermal tumor (PNET)2 (5.7%)
 Retinoblastoma2 (5.7%)
 Ewing’s sarcoma2 (5.7%)
 Chronic myeloid leukemia1 (2.9%)
 Other solid tumors9 (25.7%)
Received filgrastim19 (54.2%)
Days receiving filgrastim before day 1 of the study (mean, range)4.5 (1–7)
Low risk11 (31.5%)
High risk (hospitalized)24 (68.5%)