Cytokine Kinetics in Febrile Neutropenic Children: Insights on the Usefulness as Sepsis Biomarkers, Influence of Filgrastim, and Behavior of the IL-23/IL-17 Pathway

Table 5

Medians of biomarkers (pg/mL) on the day 1 of fever in patients receiving filgrastim or not. Mann–Whitney and median tests; ^‡Mann–Whitney test; ^†determined by Monte Carlo simulation with 10,000 tables.

	Filgrastim	No filgrastim		99% CI^†
G-CSF	5838	302.9	0.000	0.000-0.000
IL-8	155.4	58.2	0.011^‡	0.006–0.011
IL-6	132	39.5	0.007	0.003–0.007
IL-10	5.51	1.2	0.004^‡	0.002–0.04
PCT	223.3	98.1	0.07^‡	0.06–0.08