Cytokine Kinetics in Febrile Neutropenic Children: Insights on the Usefulness as Sepsis Biomarkers, Influence of Filgrastim, and Behavior of the IL-23/IL-17 Pathway

Table 6

Performance of IL-6, IL-8, PCT, and IL-10 for discrimination of sepsis on day 1 of fever. AUC: area under the ROC curve.

	AUC	Standard error		95% CI (sample)	95% CI (Bootstrap)	Youden (J)
IL-6	0.87	0.062	0.000	0.75–0.99	0.76–0.8	0.65
IL-8	0.86	0.074	0.000	0.72–1	0.83–0.87	0.7
PCT	0.89	0.054	0.000	0.78–0.99	0.87–0.90	0.64
IL-10	0.83	0.08	0.001	0.67–0.98	0.79–0.83	0.6