Human β-Defensin 3 Reduces TNF-α-Induced Inflammation and Monocyte Adhesion in Human Umbilical Vein Endothelial Cells

Figure 2

Effects of hBD3 on IL-8, IL-6, MCP-1, and MIF production in TNF-α-stimulated HUVECs. Cells were incubated with TNF-α (40 ng/mL) with or without various concentrations of hBD3 for 24 h. Then, the culture supernatants were collected by centrifugation and analyzed by ELISA according to the manufacturer’s instructions. Data are expressed as the mean ± SD (). compared with the control group. , , and compared with TNF-α group.

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