Immune Checkpoint Receptors Tim-3 and PD-1 Regulate Monocyte and T Lymphocyte Function in Septic Patients

Figure 1

Tim-3 and PD-1 expression in 23 sepsis patients and 20 HC by flow cytometry. (a) Flow cytometry gating strategy for the determination of Tim-3(+) and PD-1(+) on T cells. (b) The percentages of CD3+Tim-3+, CD3+CD4+Tim-3+, and CD3+CD8+Tim-3+ T cells. (c) The percentages of CD3+PD-1+, CD3+CD4+PD-1+, and CD3+CD8+PD-1+ T cells. Statistical analysis was performed by the Mann–Whitney test.

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