Immune Checkpoint Receptors Tim-3 and PD-1 Regulate Monocyte and T Lymphocyte Function in Septic Patients

Table 1

The demographic and clinical characteristics of subjects.

Variables	Patients with sepsis ()	Healthy controls ()
Age (year)	57.30 ± 10.18	54.40 ± 10.26	0.358^#
Male (%)	69.57%	65.00%	0.75^†
WBC	13.86 ± 6.58	5.74 ± 1.00	<0.001^Δ
(absolute lymphocyte count)	0.90 ± 0.32	1.90 ± 0.38	<0.001^Δ
Lymphocyte (%)	7.40 ± 2.90	30.21 ± 4.34	<0.001^Δ
Monocytes (%)	0.54 ± 0.30	0.50 ± 0.23	0.88^Δ
APACHE II	21.94 ± 8.09	—	—
Length of ICU stay	18.78 ± 17.27	—	—
Mortality	7	—	—
SOFA (sequential organ failure assessment)	11.65 ± 5.01	—	—

Data shown are mean ± SD. was considered statistically significant. ^#One-way ANOVA test; ^†Pearson chi-square test; ^ΔMann–Whitney nonparametric test.