Anti-TNF-α Therapy Suppresses Proinflammatory Activities of Mucosal Neutrophils in Inflammatory Bowel Disease

Figure 6

Anti-TNF-α therapy promotes apoptosis of neutrophils in active CD patients. (a–c) Peripheral neutrophils were isolated from healthy donors (), patients with active CD (), and patients with active UC () and incubated with HIg (50 μg/ml), IFX (50 μg/ml), or TNF-α (20 ng/ml) for 24 h. Cells were collected and detected for apoptosis by flow cytometry. .

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