Anti-TNF-α Therapy Suppresses Proinflammatory Activities of Mucosal Neutrophils in Inflammatory Bowel Disease

Table 1

Clinical characteristics of IBD patients.

	Blood			Intestinal biopsy
	HC	CD (A/R)^b	UC (A/R)^b	HC	CD (A/R)^b	UC (A/R)^b
Patients	24	26/22	28/16	10	15/7	12/0
Age (yrs)	52.5 ± 18	25.6 ± 6.8	41 ± 10	48.7 ± 17.4	24.7 ± 5.6	41.6 ± 11.7
Gender (F/M)	15/9	28/20	26/16	4/6	12/10	4/6
Duration (months)		28 ± 26.7	63.6 ± 46.2		27.5 ± 32	46.8 ± 28.5
Current therapy
5-ASA		39	40		22	10
Immunosuppressants		27	14		5	4
Biologics		0	0		0	0
Disease extent^a
E1			5
E2			22			3
E3			17			9
Disease location^a
L1		4			0
L2		16			5
L3		28			17
L4		0			0

^aMontreal classification; ^bA/R, active/remission.