Upregulation of Cardiac IL-10 and Downregulation of IFN-γ in Balb/c IL-4^−/− in Acute Chagasic Myocarditis due to Colombian Strain of Trypanosoma cruzi

Figure 3

Cytokine expression with regulatory profile in cardiac tissue and serum of Balb/c WT and Balb/c IL-4^−/− mice infected and not infected with the T. cruzi Colombian strain in the acute phase of experimental Chagas’ disease. (a) Production of IL-10 in cardiac tissue (pg/g) and (b) serum levels of IL-10 (pg/ml). (c) Production of IL-17 in cardiac tissue (pg/g). Student’s -test. Bars represent the mean, and vertical lines represent the standard error. Significant differences between infected versus uninfected animals. ^ΔSignificant differences between the WT versus IL-4^−/− group.

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