Involvement of M1 Macrophage Polarization in Endosomal Toll-Like Receptors Activated Psoriatic Inflammation

<div>Induction of cytokine production by endogenous Toll-like receptor (TLR) 7–9 ligands. (a) THP-1 macrophages and (b) bone marrow-derived macrophages were treated with 2 <i>μ</i>g/mL LL37, LL37/DNA, or LL37/RNA complex for 24 h. Production of cytokines was determined by quantitative real-time polymerase chain reaction (RT-qPCR) analysis. 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Mediators of Inflammation

fig6

Figure 6

Figure 6: Involvement of M1 Macrophage Polarization in Endosomal Toll-Like Receptors Activated Psoriatic Inflammation 