Shock Wave Therapy Enhances Mitochondrial Delivery into Target Cells and Protects against Acute Respiratory Distress Syndrome

Figure 8

Histopathological findings of lung parenchyma by day 5 after ARDS induction. (a to e) Illustrating the microscopic finding (200x) of Sirius red stain for identification of condensed collagen deposition in lung parenchyma. (f) Analytical result of condensed collagen deposition area, versus other groups with different symbols (†, ‡, §, ¶), . (g to k) Illustrating the microscopic finding (200x) of Masson’s trichrome stain for identification of fibrosis in lung parenchyma. (l) Analytical result of fibrotic area, versus other groups with different symbols (†, ‡, §, ¶), . The scale bars in the right lower corner represent 50 μm. All statistical analyses were performed by one-way ANOVA, followed by Bonferroni multiple comparison post hoc test. Symbols (, †, ‡, §, ¶) indicate significance (at 0.05 level). SC = sham control; ARDS = acute respiratory distress syndrome; Mito = mitochondria; SW = shock wave.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)

(k)

(l)