Transcriptional Profiling Suggests Extensive Metabolic Rewiring of Human and Mouse Macrophages during Early Interferon Alpha Responses

<div>IFN-<i>α</i> stimulation of MDM is associated with increased expression of genes associated with ROS production and antioxidant responses. 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Green and red represent genes that have been significantly upregulated or downregulated, respectively. Blue represents genes that were not altered following IFN-<i>α</i> stimulation.</div>

Mediators of Inflammation

fig4

Figure 4

Figure 4: Transcriptional Profiling Suggests Extensive Metabolic Rewiring of Human and Mouse Macrophages during Early Interferon Alpha Responses 